Incense is psychoactive: Scientists identify the biology behind the ceremony

Incense is psychoactive: Scientists identify the biology behind the ceremony:

“In spite of information stemming from ancient texts, constituents of Bosweilla had not been investigated for psychoactivity,” said Raphael Mechoulam, one of the research study’s co-authors. “We found that incensole acetate, a Boswellia resin constituent, when tested in mice lowers anxiety and causes antidepressive-like behavior. Apparently, most present day worshipers assume that incense burning has only a symbolic meaning.”

To determine incense’s psychoactive effects, the researchers administered incensole acetate to mice. They found that the compound significantly affected areas in brain areas known to be involved in emotions as well as in nerve circuits that are affected by current anxiety and depression drugs. Specifically, incensole acetate activated a protein called TRPV3, which is present in mammalian brains and also known to play a role in the perception of warmth of the skin. When mice bred without this protein were exposed to incensole acetate, the compound had no effect on their brains.

“Perhaps Marx wasn’t too wrong when he called religion the opium of the people: morphine comes from poppies, cannabinoids from marijuana, and LSD from mushrooms; each of these has been used in one or another religious ceremony.” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “Studies of how those psychoactive drugs work have helped us understand modern neurobiology. The discovery of how incensole acetate, purified from frankincense, works on specific targets in the brain should also help us understand diseases of the nervous system. This study also provides a biological explanation for millennia-old spiritual practices that have persisted across time, distance, culture, language, and religion—burning incense really does make you feel warm and tingly all over!”

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Plant flavonoid found to reduce inflammatory response in the brain

Plant flavonoid found to reduce inflammatory response in the brain

Inflammation can be a blessing or a blight. It is a critical part of the body’s immune response that in normal circumstances reduces injury and promotes healing. When it goes awry, however, the inflammatory response can lead to serious physical and mental problems.

Inflammation plays a key role in many neurodegenerative diseases and also is implicated in the cognitive and behavioral impairments seen in aging.

The new study looked at luteolin (LOO-tee-OH-lin), a plant flavonoid known to impede the inflammatory response in several types of cells outside the central nervous system. The purpose of the study was to determine if luteolin could also reduce inflammation in the brain, said animal sciences professor and principal investigator Rodney Johnson.

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Think Positive, and You Will Get Smarter

Think Positive, and You Will Get Smarter

Learning new things actually strengthens your brain — especially when you believe you can learn new things. It's a virtuous circle: When you think you're getting smarter, you study harder, making more nerve-cell connections, which in turn makes you ... smarter. This effect shows up consistently among experimental subjects, from seventh graders to college students to businesspeople. According to studies carried out by Stanford University psychology professor Carol Dweck and others, volunteers with a so-called growth mindset about learning ("persist in the face of setbacks") have more brain plasticity. In other words, their noggins are more adaptable. They exhibit increases in cognitive performance compared with those who have a so-called fixed mindset ("get defensive or give up easily"). "Many people believe they have a fixed level of intelligence, and that's that," Dweck says. "The cure is to change the mindset." Certain that we're wrong? Enjoy stupidity!

Technorati tags: learning, intelligence