Technology has immortality, cures for the worlds devastating diseases, quantum computing and a host of other science fiction notions in its grasp. Current trends in a number of areas indicate that over the next 10 years many of these technologies will come to fruition. "The Next 10 Years" tracks the trends that will transform our everyday lives in almost unimaginable ways.

Thursday, November 29, 2007

Technology Review: The Longevity Pill?

Technology Review: The Longevity Pill?

A novel group of drugs that target a gene linked to longevity could provide a way to turn back the clock on the diseases of aging. The compounds are 1,000 times more potent than resveratrol, the molecule thought to underlie the health benefits of red wine, and have shown promise in treating rodent models of obesity and diabetes.
Human clinical trials to test the compounds in diabetes are slated to begin early next year, according to Sirtris Pharmaceuticals, based in Cambridge, MA, which developed the drugs. "As far as I'm aware, this is the first anti-aging molecule going into [testing in] man," says David Sinclair, a biologist at Harvard Medical School, in Boston, and cofounder of Sirtris. (See "The Enthusiast.") "From that standpoint, this is a major milestone in medicine."

tags: sirtuin activators, longevity, sirt1 activators

Saturday, November 17, 2007

Wormholes on Earth?

Wormholes on Earth?

According to a group of mathematicians, it may be possible to create devices with internal tunnels that are invisible to detection by electromagnetic waves—wormholes, in a sense. The group discusses the idea in a paper published in the October 29 online edition of Physical Review Letters.

The scientists say that by custom designing the values of two parameters that describe electromagnetic (EM) materials, the electrical permittivity and magnetic permeability, around and inside a cylinder, a novel optical device could be produced. Essentially, most of the device would be invisible to detection by external EM radiation of a certain frequency, with only the ends of the cylinder being visible and accessible to the EM waves.


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My Genome, Myself: Seeking Clues in DNA - New York Times

My Genome, Myself: Seeking Clues in DNA - New York Times:
The exploration of the human genome has long been relegated to elite scientists in research laboratories. But that is about to change. An infant industry is capitalizing on the plunging cost of genetic testing technology to offer any individual unprecedented — and unmediated — entree to their own DNA.

For as little as $1,000 and a saliva sample, customers will be able to learn what is known so far about how the billions of bits in their biological code shape who they are. Three companies have already announced plans to market such services, one yesterday.

Offered the chance to be among the early testers, I agreed, but not without reservations. What if I learned I was likely to die young? Or that I might have passed on a rogue gene to my daughter? And more pragmatically, what if an insurance company or an employer used such information against me in the future?


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Friday, November 16, 2007

Is mathematical pattern the theory of everything? - fundamentals - 17 November 2007 - New Scientist

Is mathematical pattern the theory of everything? - fundamentals - 17 November 2007 - New Scientist


GARRETT LISI is an unlikely individual to be staking a claim for a theory of everything. He has no university affiliation and spends most of the year surfing in Hawaii. In winter, he heads to the mountains near Lake Tahoe, California, to teach snowboarding. Until recently, physics was not much more than a hobby.

That hasn't stopped some leading physicists sitting up and taking notice after Lisi made his theory public on the physics pre-print archive this week (www.arxiv.org/abs/0711.0770). By analysing the most elegant and intricate pattern known to mathematics, Lisi has uncovered a relationship underlying all the universe's particles and forces, including gravity - or so he hopes. Lee Smolin at the Perimeter Institute for Theoretical Physics (PI) in Waterloo, Ontario, Canada, describes Lisi's work as "fabulous". "It is one of the most compelling unification models I've seen in many, many years," he says.

That's some achievement, as physicists have been trying to find a uniform framework for the fundamental forces and particles ever since they developed the standard model more than 30 years ago. The standard model successfully weaves together three of the four fundamental forces of nature: the electromagnetic force; the strong force, which binds quarks together in atomic nuclei; and the weak force, which controls radioactive decay. The problem has been that gravity has so far refused to join the party.

For decades, physicists have been trying to find a uniform framework for the fundamental forces and particles

Most attempts to bring gravity into the picture have been based on string theory, which proposes that particles are ultimately composed of minuscule strings. Lisi has never been a fan of string theory and says that it's because of pressure to step into line that he abandoned academia after his PhD. "I've never been much of a follower, so I walked off to search for my own theory," he says. Last year, he won a research grant from the charitably funded Foundational Questions Institute to pursue his ideas.

He had been tinkering with "weird" equations for years and getting nowhere, but six months ago he stumbled on a research paper analysing E8 - a complex, eight-dimensional mathematical pattern with 248 points. He noticed that some of the equations describing its structure matched his own. "The moment this happened my brain exploded with the implications and the beauty of the thing," says Lisi. "I thought: 'Holy crap, that's it!'"


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